|By PR Newswire||
|January 15, 2013 07:00 AM EST||
FOSTER CITY, Calif., Jan. 15, 2013 /PRNewswire/ -- Silicon Valley Biosystems (SV Bio), a diagnostics company founded to provide rapid, accurate, and turnkey clinical interpretation of comprehensive genomics data at the point of care to improve the health and outcomes of patients, was launched today. Backed by Sequoia Capital, a premier venture capital firm that helped to build Apple, Google, LinkedIn, Oracle and numerous biotech companies, SV Bio is ushering in the next phase of genomics-based medicine by providing clinicians with the tools they need to make faster, more precise and cost-saving decisions.
"The transition is occurring very rapidly nowadays from genomics as a science to genomics as a key driver of clinical medicine and decision-making at the bedside," noted Dietrich Stephan, Ph.D., SV Bio founder and CEO. "As genomic sequencing costs plummet, the potential clinical impact soars. SV Bio is building the requisite bridge from the genomics bench to the bedside, assisting physicians with the accurate and actionable interpretation they need for optimizing care for each individual."
Up to now, clinical adoption of genomic technologies has been hampered by the deluge of data, the difficulty of analysis in real-time, and the difficulty of integrating research technologies into the clinical setting. SV Bio intends to accelerate that adoption, by making it simple and easy for all types of physicians and large health care providers.
"SV Bio really sees the world through the eyes of the clinician. To us, the word 'actionable' means finding a precise diagnosis for a case; reducing risk for family members; and predicting if treatments will be effective or futile," said Tim Triche, M.D., Ph.D., a clinician with 30 years of scientific and medical experience at pioneering companies including OncorMed, Genelogic, and GenomeDx and also Chairman of Pathology at Children's Hospital of Los Angeles, who serves on the company's Board of Directors. "It takes data currently available but cumbersome and challenging to use, and delivers it in a format that is more easily interpreted by the physician and applicable to individualized patient care."
A Rapid, Easy to Use Decision Support Tool for Clinicians
SV Bio's turnkey genomics interpretation services query the patient's genome at the point of care and distill the biological data into a concise, actionable report that medical generalists and specialists can easily use as a decision support tool.
The SV Bio platform fits into current clinical workflows and is able to take data from any next generation sequencer and determine with clinical grade sensitivity and specificity which genetic variants within a patient's DNA sequence are influencing a disease or condition. The resulting clinical reports are fast—taking only minutes to complete from sample sequence to delivery of the report to the physician—and are presented in a format that makes it easy for practitioners to read, interpret and apply to patient care.
Early Success Identifying Underlying Causes of Mystery Conditions
Many patients have already been helped by SV Bio diagnostic services. One recent case involved a family with two affected children who were initially thought to have autism spectrum disorder due to their language regression, IQ drops and seizures at 2 years of age. Subsequent neurodegenerative decline puzzled physicians at leading medical institutions and triggered a multi-year odyssey of clinical workups and focused genetic testing. Ultimately, the physicians turned to SV Bio, where the patient genomes were sequenced and the underlying genetic mutation in a gene named TPP1 was uncovered immediately. The gene defect causes the extremely rare disease late-infantile neuronal ceroid lipofuscinosis that is fatal by 8 years of age. The mutation was verified biochemically to be causative of the disorder, and allowed the children to gain access to a clinical trial that has shown promising results at halting the progression of the disease – a trial to which they would never have turned for a solution to a fatal disease in the absence of a specific molecular diagnosis.
"This is the new wave of genomics medicine; one that we expect to set new precedents and have a major impact on healthcare overall," said Dr. Triche.
SV Bio is currently providing diagnostic testing services to physicians and centers of excellence for all heritable genetic conditions. These services include testing single genes and bundled gene sets for disorders which are genetically heterogeneous and for which the causative genes are known. In addition, testing of the entire genome is available for mystery illnesses or in cases where other diagnostic companies could not return a definitive result because the causative gene is not known, or in cases where a variant was detected but could not be classified as causative. SV Bio uses sophisticated classification technology to provide the highest precision of pathogenicity prediction for variants, which have not been seen before - increasing sensitivity when coupled with the highest quality next-generation sequencing of the entire genome. Testing can be obtained by contacting SV Bio at [email protected].
About SV Bio
SV Bio is a diagnostics company, founded to provide rapid, accurate, turnkey clinical interpretation of comprehensive genomics data at point of care to improve the health and outcomes of patients. The Company was founded by Dietrich A. Stephan, Ph.D., who has dedicated his career to the development of genomics-based precision medicine and has gathered a multi-disciplinary team of experts in genomics, statistics, bioinformatics, and machine learning. SV Bio is backed by Sequoia Capital, a premier venture capital firm that helped to build Apple, Google, LinkedIn, Oracle and numerous other technology-based firms. SV Bio's Board of Directors includes Timothy Triche, M.D., Ph.D., of the Center for Personalized Medicine, Children's Hospital Los Angeles; Warren Hogarth, Ph.D., M.B.A., a partner at Sequoia Capital; Todd Cozzens, M.B.A., formerly of Picis, who serves as SV Bio's Chairman; and Jeremy Friese, M.D., M.B.A., who leads business development, finance and practices medicine at the Mayo Clinic. For more information, please visit www.svbio.com.
SOURCE SV Bio
SYS-CON Events announced today that Peak 10, Inc., a national IT infrastructure and cloud services provider, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Peak 10 provides reliable, tailored data center and network services, cloud and managed services. Its solutions are designed to scale and adapt to customers’ changing business needs, enabling them to lower costs, improve performance and focus inter...
May. 3, 2016 12:00 PM EDT Reads: 1,339
Artificial Intelligence has the potential to massively disrupt IoT. In his session at 18th Cloud Expo, AJ Abdallat, CEO of Beyond AI, will discuss what the five main drivers are in Artificial Intelligence that could shape the future of the Internet of Things. AJ Abdallat is CEO of Beyond AI. He has over 20 years of management experience in the fields of artificial intelligence, sensors, instruments, devices and software for telecommunications, life sciences, environmental monitoring, process...
May. 3, 2016 11:30 AM EDT Reads: 1,090
The increasing popularity of the Internet of Things necessitates that our physical and cognitive relationship with wearable technology will change rapidly in the near future. This advent means logging has become a thing of the past. Before, it was on us to track our own data, but now that data is automatically available. What does this mean for mHealth and the "connected" body? In her session at @ThingsExpo, Lisa Calkins, CEO and co-founder of Amadeus Consulting, will discuss the impact of wea...
May. 3, 2016 11:30 AM EDT Reads: 873
There is an ever-growing explosion of new devices that are connected to the Internet using “cloud” solutions. This rapid growth is creating a massive new demand for efficient access to data. And it’s not just about connecting to that data anymore. This new demand is bringing new issues and challenges and it is important for companies to scale for the coming growth. And with that scaling comes the need for greater security, gathering and data analysis, storage, connectivity and, of course, the...
May. 3, 2016 11:15 AM EDT Reads: 1,015
We’ve worked with dozens of early adopters across numerous industries and will debunk common misperceptions, which starts with understanding that many of the connected products we’ll use over the next 5 years are already products, they’re just not yet connected. With an IoT product, time-in-market provides much more essential feedback than ever before. Innovation comes from what you do with the data that the connected product provides in order to enhance the customer experience and optimize busi...
May. 3, 2016 11:00 AM EDT Reads: 1,135
The IoTs will challenge the status quo of how IT and development organizations operate. Or will it? Certainly the fog layer of IoT requires special insights about data ontology, security and transactional integrity. But the developmental challenges are the same: People, Process and Platform. In his session at @ThingsExpo, Craig Sproule, CEO of Metavine, will demonstrate how to move beyond today's coding paradigm and share the must-have mindsets for removing complexity from the development proc...
May. 3, 2016 10:30 AM EDT Reads: 559
Increasing IoT connectivity is forcing enterprises to find elegant solutions to organize and visualize all incoming data from these connected devices with re-configurable dashboard widgets to effectively allow rapid decision-making for everything from immediate actions in tactical situations to strategic analysis and reporting. In his session at 18th Cloud Expo, Shikhir Singh, Senior Developer Relations Manager at Sencha, will discuss how to create HTML5 dashboards that interact with IoT devic...
May. 3, 2016 10:30 AM EDT Reads: 1,183
SYS-CON Events announced today that Ericsson has been named “Gold Sponsor” of SYS-CON's @ThingsExpo, which will take place on June 7-9, 2016, at the Javits Center in New York, New York. Ericsson is a world leader in the rapidly changing environment of communications technology – providing equipment, software and services to enable transformation through mobility. Some 40 percent of global mobile traffic runs through networks we have supplied. More than 1 billion subscribers around the world re...
May. 3, 2016 10:15 AM EDT Reads: 1,172
So, you bought into the current machine learning craze and went on to collect millions/billions of records from this promising new data source. Now, what do you do with them? Too often, the abundance of data quickly turns into an abundance of problems. How do you extract that "magic essence" from your data without falling into the common pitfalls? In her session at @ThingsExpo, Natalia Ponomareva, Software Engineer at Google, will provide tips on how to be successful in large scale machine lear...
May. 3, 2016 09:45 AM EDT Reads: 1,405
In his session at @ThingsExpo, Chris Klein, CEO and Co-founder of Rachio, will discuss next generation communities that are using IoT to create more sustainable, intelligent communities. One example is Sterling Ranch, a 10,000 home development that – with the help of Siemens – will integrate IoT technology into the community to provide residents with energy and water savings as well as intelligent security. Everything from stop lights to sprinkler systems to building infrastructures will run ef...
May. 3, 2016 08:30 AM EDT Reads: 1,104
You think you know what’s in your data. But do you? Most organizations are now aware of the business intelligence represented by their data. Data science stands to take this to a level you never thought of – literally. The techniques of data science, when used with the capabilities of Big Data technologies, can make connections you had not yet imagined, helping you discover new insights and ask new questions of your data. In his session at @ThingsExpo, Sarbjit Sarkaria, data science team lead ...
May. 3, 2016 07:00 AM EDT Reads: 1,063
You deployed your app with the Bluemix PaaS and it's gaining some serious traction, so it's time to make some tweaks. Did you design your application in a way that it can scale in the cloud? Were you even thinking about the cloud when you built the app? If not, chances are your app is going to break. Check out this webcast to learn various techniques for designing applications that will scale successfully in Bluemix, for the confidence you need to take your apps to the next level and beyond.
May. 2, 2016 12:00 PM EDT Reads: 1,574
SYS-CON Events announced today that Fusion, a leading provider of cloud services, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Fusion, a leading provider of integrated cloud solutions to small, medium and large businesses, is the industry's single source for the cloud. Fusion's advanced, proprietary cloud service platform enables the integration of leading edge solutions in the cloud, including cloud...
May. 2, 2016 10:00 AM EDT Reads: 2,675
Digital payments using wearable devices such as smart watches, fitness trackers, and payment wristbands are an increasing area of focus for industry participants, and consumer acceptance from early trials and deployments has encouraged some of the biggest names in technology and banking to continue their push to drive growth in this nascent market. Wearable payment systems may utilize near field communication (NFC), radio frequency identification (RFID), or quick response (QR) codes and barcodes...
May. 2, 2016 09:15 AM EDT Reads: 906
SYS-CON Events announced today that DatacenterDynamics has been named “Media Sponsor” of SYS-CON's 18th International Cloud Expo, which will take place on June 7–9, 2016, at the Javits Center in New York City, NY. DatacenterDynamics is a brand of DCD Group, a global B2B media and publishing company that develops products to help senior professionals in the world's most ICT dependent organizations make risk-based infrastructure and capacity decisions.
May. 2, 2016 06:30 AM EDT Reads: 2,564
The IoT has the potential to create a renaissance of manufacturing in the US and elsewhere. In his session at 18th Cloud Expo, Florent Solt, CTO and chief architect of Netvibes, will discuss how the expected exponential increase in the amount of data that will be processed, transported, stored, and accessed means there will be a huge demand for smart technologies to deliver it. Florent Solt is the CTO and chief architect of Netvibes. Prior to joining Netvibes in 2007, he co-founded Rift Technol...
May. 1, 2016 11:00 PM EDT Reads: 1,636
SYS-CON Events announced today that Stratoscale, the software company developing the next generation data center operating system, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Stratoscale is revolutionizing the data center with a zero-to-cloud-in-minutes solution. With Stratoscale’s hardware-agnostic, Software Defined Data Center (SDDC) solution to store everything, run anything and scale everywhere...
May. 1, 2016 01:30 PM EDT Reads: 1,621
Angular 2 is a complete re-write of the popular framework AngularJS. Programming in Angular 2 is greatly simplified – now it's a component-based well-performing framework. This immersive one-day workshop at 18th Cloud Expo, led by Yakov Fain, a Java Champion and a co-founder of the IT consultancy Farata Systems and the product company SuranceBay, will provide you with everything you wanted to know about Angular 2.
May. 1, 2016 01:00 PM EDT Reads: 1,799
SYS-CON Events announced today that Men & Mice, the leading global provider of DNS, DHCP and IP address management overlay solutions, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. The Men & Mice Suite overlay solution is already known for its powerful application in heterogeneous operating environments, enabling enterprises to scale without fuss. Building on a solid range of diverse platform support,...
May. 1, 2016 12:15 PM EDT Reads: 2,377
Whether your IoT service is connecting cars, homes, appliances, wearable, cameras or other devices, one question hangs in the balance – how do you actually make money from this service? The ability to turn your IoT service into profit requires the ability to create a monetization strategy that is flexible, scalable and working for you in real-time. It must be a transparent, smoothly implemented strategy that all stakeholders – from customers to the board – will be able to understand and comprehe...
May. 1, 2016 11:00 AM EDT Reads: 1,141